Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease

Author(s):
Awoniyi, D.O.; Teuchert, A.; Sutherland, J.S.; Mayanja-Kizza, H.; Howe, R.; Mihret, A.; Loxton, A.G.; Sheehama, J.; Kassa, D.; Crampin, A.C.; Dockrell, H.M.; Kidd, M.; Rosenkrands, I.; Geluk, A. (0000-0001-8555-2872); Ottenhoff, T.H.M. (0000-0003-3706-3403); Corstjens, P.L.A.M.; Chegou, N.N.; Walzl, G.; AE-TBC Consortium
Published
2016
Publication type
Article / Letter to editor

Abstract

Conclusions: A biosignature of 6 cytokines obtained after stimulation with four Mtb antigens has moderate potential as a diagnostic tool for pulmonary TB disease individuals and stimulated marker expression had no added value to unstimulated marker performance. (C) 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

BiosignatureHost markersAntigen
Date issued
2016-09-01
Language
English
Publisher
W B SAUNDERS CO LTD
Is part of
Journal of Infection (2016), Vol. 73, no. 3, p. 219-230
hdl
1887/99425
doi
10.1016/j.jinf.2016.04.036