Trichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in immunocompromised patients

Author(s):
Rouanet, J.; Aubin, F.; Gaboriaud, P.; Berthon, P.; Feltkamp, M.C.; Bessenay, L.; Touze, A.; Nicol, J.T.J.; Franck, F.; D'Incan, M.
Published
2016
Publication type
Article / Letter to editor

Abstract

Trichodysplasia spinulosa (TS) is a rare skin disease, caused by a specific polyomavirus, occurring in immunocompromised patients. The pathophysiological mechanisms of TS are not yet fully understood. By using polymerase chain reaction and skin biopsy immunostaining we report evidence, in a paediatric case, of follicular keratinocytes being the primary target of trichodysplasia spinulosa-associated polyomavirus.

Date issued
2016-03-01
Language
English
Publisher
WILEY-BLACKWELL
Is part of
British Journal of Dermatology (2016), Vol. 174, no. 3, p. 629-632
hdl
1887/99373
doi
10.1111/bjd.14346