17D yellow fever vaccine elicits comparable long-term immune responses in healthy individuals and immune-compromised patients

Author(s):
Wieten, R.W.; Goorhuis, A.; Jonker, E.F.F.; Bree, G.J. de; Visser, A.W. de; Genderen, P.J.J. van; Remmerswaal, E.B.M.; Berge, I.J.M. ten; Visser, L.G. (0000-0002-3600-9782); Grobusch, M.P.; Leeuwen, E.M.M. van
Published
2016
Publication type
Article / Letter to editor

Abstract

Conclusion: These results imply that YF vaccination is effective despite certain immunosuppressive drug regimens. An early-differentiated memory-like phenotype persisted, which is associated with effective expansion upon re-encounter with antigen, suggesting a potent memory T-cell pool remains. (C) 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

17D yellow feverVaccinationImmune-compromised
Date issued
2016-06-01
Language
English
Publisher
W B SAUNDERS CO LTD
Is part of
Journal of Infection (2016), Vol. 72, no. 6, p. 713-722
hdl
1887/99366
doi
10.1016/j.jinf.2016.02.017