FluxModeCalculator: an efficient tool for large-scale flux mode computation

Author(s):
Klinken, J.B. van; Dijk, K.W. van
Published
2016
Publication type
Article / Letter to editor

Abstract

Elementary flux mode (EFM) analysis is a powerful technique for determining the metabolic capacities and robustness of stoichiometric networks. Recently, several improvements have been made to the algorithm for enumerating the EFMs, making the study of large models possible. However, currently these tools require high performance workstations to perform large-scale EFM computations, thus limiting their applicability. We developed a more time and memory efficient implementation of the algorithm for EFM enumeration in MATLAB, called FluxModeCalculator, which enables large-scale EFM computation on ordinary desktop computers.

Date issued
2016-04-15
Language
English
Publisher
OXFORD UNIV PRESS
Is part of
Bioinformatics (2016), Vol. 32, no. 8, p. 1265-1266
hdl
1887/99348
doi
10.1093/bioinformaticsibtv742