Treatment of Pneumocystis pneumonia with intermediate-dose and step-down to low-dose trimethoprim-sulfamethoxazole: lessons from an observational cohort study

Abstract

We observed high cure rates of PCP by treatment with intermediate-dose TMP-SMX. In addition, a step-down strategy to low-dose TMP-SMX during treatment in selected patients appears to be safe and does not compromise the outcome of treatment.

Pneumocystis jiroveciiTreatmentLow doseCotrimoxazoleTrimethoprim-sulfamethoxazoleAntibiotic stewardship