A blood RNA signature for tuberculosis disease risk: a prospective cohort study

Author(s):
Zak, D.E.; Penn-Nicholson, A.; Scriba, T.J.; Thompson, E.; Suliman, S.; Amon, L.M.; Mahomed, H.; Erasmus, M.; Whatney, W.; Hussey, G.D.; Abrahams, D.; Kafaar, F.; Hawkridge, T.; Verver, S.; Hughes, E.J.; Ota, M.; Sutherland, J.; Howe, R.; Dockrell, H.M.; Boom, W.H.; Thiel, B.; Ottenhoff, T.H.M. (0000-0003-3706-3403); Mayanja-Kizza, H.; Crampin, A.C.; Downing, K.; Hatherill, M.; Valvo, J.; Shankar, S.; Parida, S.K.; Kaufmann, S.H.E.; Walzl, G.; Aderem, A.; Hanekom, W.A.; ACS Cohort Study Grp; GC6-74 Cohort Study Grp
Published
2016
Publication type
Article / Letter to editor

Abstract

Interpretation The whole blood tuberculosis risk signature prospectively identified people at risk of developing active tuberculosis, opening the possibility for targeted intervention to prevent the disease.

Date issued
2016-06-04
Language
English
Publisher
ELSEVIER SCIENCE INC
Is part of
Lancet (2016), Vol. 387, no. 10035, p. 2312-2322
hdl
1887/99329
doi
10.1016/S0140-6736(15)01316-1