A Single 17D Yellow Fever Vaccination Provides Lifelong Immunity; Characterization of Yellow-Fever-Specific Neutralizing Antibody and T-Cell Responses after Vaccination

Author(s):
Wieten, R.W.; Jonker, E.F.F.; Leeuwen, E.M.M. van; Remmerswaal, E.B.M.; Berge, I.J.M. ten; Visser, A.W. de; Genderen, P.J.J. van; Goorhuis, A.; Visser, L.G. (0000-0002-3600-9782); Grobusch, M.P.; Bree, G.J. de
Published
2016
Publication type
Article / Letter to editor

Abstract

The presence of a functionally competent YF-specific memory T-cell pool 18 years and sufficient titers of neutralizing antibodies 35-40 years after first vaccination suggest that single vaccination may be sufficient to provide long-term immunity.

Date issued
2016-03-15
Language
English
Publisher
PUBLIC LIBRARY SCIENCE
Is part of
PLoS ONE (2016), No. 3
hdl
1887/99323
doi
10.1371/journal.pone.0149871