Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

Author(s):
Buchan, S.L.; Dou, L.; Remer, M.; Booth, S.G.; Dunn, S.N.; Lai, C.; Semmrich, M.; Teige, I.; Martensson, L.; Penfold, C.A.; Chan, H.T.C.; Willoughby, J.E.; Mockridge, C.I.; Dahal, L.N.; Cleary, K.L.S.; James, S.; Rogel, A.; Kannisto, P.; Jernetz, M.; Williams, E.L.; Healy, E.; Verbeek, J.S.; Johnson, P.W.M.; Frendeus, B.; Cragg, M.S.; Glennie, M.J.; Gray, J.C.; Al-Shamkhani, A.; Beers, S.A.
Published
2018
Publication type
Article / Letter to editor
Date issued
2018-11-20
Language
English
Is part of
Immunity (2018), Vol. 49, no. 5, p. 958-+
hdl
1887/95926
doi
10.1016/j.immuni.2018.09.014