Microcoil MRI of plants and algae at ultra-high field : an exploration of metabolic imaging

Schadewijk, R. van (2020)

Doctoral Thesis

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI). Two model systems are studied: Botryococcus braunii, a green oleaginous algae and Medicago truncatula, a small leguminous plant in symbiosis with Sinorhizobium meliloti bacteria. In order to map the variation of metabolic profiles across tissues, MRI is used extensively, including Chemical Shift Imaging, Magnetic Resonance Spectroscopy and Diffusion-Weigthed Imaging. Home-built microcoils for ultra-high magnetic field strength are developed for studying the model organisms. 

• Magnetic Resonance Imaging
• Magnetic Resonance Microscopy
• Solenoid Microcoils
• Chemical Shift Imaging
• Magnetic Resonance Spectoscopy
• Ultra-high Field
• Botryococcus braunii
• Medicago truncatula
• Diffusion-Weighted Imaging
• Chemical Shift Selective Imaging

• All authors: Schadewijk, R. van
• Supervisor: Groot, H.J.M. de; Alia, A.
• Committee: Overkleeft, H.; Spaink, H.; Dam, N. van; Sakellariou, D.; Webb, A.; As, H. van
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University
• Date: 2020-04-30
• ISBN (print): 9789464022100