Early recognition of axial spondyloarthritis: imaging and genetic aspects

Author(s):
Bakker, P.A.C.
Published
2018
Publication type
Doctoral Thesis

Abstract

The studies described in this thesis were all centred around the same aim: the early recognition

of axial spondyloarthritis (axSpA) and a minimization of the diagnostic delay. An important

step in tackling these issues was that experts in the field have designed prospective cohort

studies in which consecutive patients with either chronic or inflammatory back pain (the latter being the most common first symptom) of short duration are included and followed up in a standardized manner with imaging performed at certain pre-set times. This allows us to obtain information on who will develop axSpA and who will not. Those cohort studies provide valuable information on the early detection and disease course of axSpA and form the basis of the research presented in this thesis.

Axial spondyloarthritisAnkylosing spondylitisMagnetic resonance imagingConventional radiographs
Defense date
2018-10-10
Language
English
Supervisor(s)
Heijde, D.M.F.M. van der
Advisor(s)
Gaalen, F.A. van; Reijnierse, M.
Committee member(s)
Bosch, F.E. van den; Tubergen, A.M. van; Huizinga, T.W.J.; Marijnen, C.A.M.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/80104
ISBN(s)
9789493014459

Funding

Sponsorship
Chipsoft BV Pfizer BV UCB BV Elekta BV