Measuring pharmacodynamics in early clinical drug studies in multiple sclerosis

Author(s):
Kanhai, K.M.S.
Published
2019
Publication type
Doctoral Thesis

Abstract

This thesis describes six clinical studies: two studies

that investigate new compounds to treat symptoms of multiple sclerosis (MS)

(chapters 2 and 3), one study that investigates a new compound to treat MS

(chapter 4) and three studies about the development of new methods to determine effects of a new class of compounds to treat MS (chapters 5, 6 and 7).

Multiple sclerosisDrug developmentBiomarkersRemyelination
Defense date
2019-10-10
Language
English
Supervisor(s)
Cohen, A.F.
Advisor(s)
Groeneveld, G.J.
Committee member(s)
Burggraaf, J.; Lange, E.C.M. de; Killestein, J.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/79260

Funding

Sponsorship
CHDR