Functional brain responses in the maintenance of energy balance

Author(s):
Opstal, A.M. van
Published
2019
Publication type
Doctoral Thesis

Abstract

This thesis describes brain function and brain responses

that play a role in the maintenance of energy balance. The responses of the

brain to various factors influencing energy balance in healthy lean

participants are described. The factors investigated include the effects of the ingestion various sugars and sweeteners, the effects of consumption temperature, the effect of added flavoring and the effect of hormones involved in energy balance. Furthermore, brain function is investigated in conditions showing a disrupted energy balance by determining brain responses in both Anorexia Nervosa and obesity.

Energy homeostasisCentral regulationEnergy ingestionFunctional brain responsesFunctional MRI
Defense date
2019-05-29
Language
English
Supervisor(s)
Rombouts, S.A.R.B.
Advisor(s)
Grond, J. van der
Committee member(s)
Lamb, H.J.; Slagboom, P.; Furth, E.F. van; Rossum, E.F.C. van
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/73638
ISBN(s)
9789463803229

Funding

Sponsorship
The research described in this thesis was funded by Unilever Research & Development, Vlaardingen, the Netherlands and by the European Commission funded projects Switchbox (FP7, Health-F2-2010-259772) and HUMAN (Health-2013-INNOVATION- 1-602757).