On the pathogenesis and clinical outcome of ANCA-associated vasculitis

Author(s):
Rahmattulla, C.
Published
2018
Publication type
Doctoral Thesis

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated

vasculitis (AAV), including granulomatosis with polyangiitis (Wegener’s)

(GPA) and microscopic polyangiitis (MPA), is a small-to-medium vessel

vasculitis that affect multiple organs and is life-threatening when untreated. In this thesis, several aspects of ANCA-associated vasculitis concerning genetics, clinical and histopathological classification, treatment and long-term outcome were investigated.

ANCA-associated vasculitisGeneticsENTGlomerulonephritisHistopathological classificationMalignancyRituximab
Defense date
2018-10-11
Language
English
Supervisor(s)
Bruijn, J.A. de
Advisor(s)
Bajema, I.M.; Berden, A.E.
Committee member(s)
Smit, V.T.H.B.M.; Reinders, M.E.J.; Rosendaal, F.R.; WIlhelmus, S.; Kronbichler, A.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/72515
ISBN(s)
9789402811698