Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach

Author(s):
Brussee, J.M. (0000-0002-0813-4463); Yu, H.; Krekels, E.H.J. (0000-0001-6006-1567); Palic, S.; Brill, M.J.E.; Barrett, J.S.; Rostami-Hodjegan, A.; Wildt, S.N. de; Knibbe, C.A.J. (0000-0001-9893-4415)
Published
2018
Publication type
Article / Letter to editor
CYP3Aextraction ratioabsorptionfirst-pass metabolismgut wallliverpediatrics
Date issued
2018-09-30
Language
English
Is part of
Pharmaceutical Research (2018), Vol. 35, p. 182
hdl
1887/70393
doi
10.1007/s11095-018-2458-6