Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

Author(s):
Calvier, E.A.M.; Thu, T.N.; Johnson, T.N.; Rostami-Hodjegan, A.; Tibboel, D.; Krekels, E.H.J. (0000-0001-6006-1567); Knibbe, C.A.J. (0000-0001-9893-4415)
Published
2018
Publication type
Article / Letter to editor
paediatricsphysiologically-based pharmacokineticpopulation modellingpopulation optimal design
Date issued
2018-11-30
Language
English
Is part of
Pharmaceutical Research (2018), Vol. 35, no. 11, p. 209
hdl
1887/70392
doi
10.1007/s11095-018-2487-1