Evaluation of donor lymphocyte infusions after allogeneic stem cell transplantation

Author(s):
Eefting, M.
Published
2018
Publication type
Doctoral Thesis

Abstract

The effect of donor lymphocyte infusions (DLI) after allogeneic stem cell transplantation is difficult to determine and currently unknown. The thesis describes different statistical methods the determine the effect of DLI after T-cell depleted allogeneic stem cell transplantation for ALL, AML, MDS, relapse AML and multiple myeloma. The effect on bone marrow disease appears strong as compared to extramudullary disease.

Allogeneic stem cell transplantationDonor lymphocyte infusionMulti-state model
Defense date
2018-12-13
Language
English
Supervisor(s)
Falkenburg, J.H.F.
Advisor(s)
Halkes, C.J.M.; Wreede, L.C. de
Committee member(s)
Zwaginga, J.J.; Zweegman, S.; Cornelissen, J.J.
Qualification
Ph.D.
Degree granting institution
Hematologie, Medicine / Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/67416
ISBN(s)
9789463611664