MRI and histologic studies on early markers of Alzheimer's disease

Author(s):
Duijn, S. van
Published
2018
Publication type
Doctoral Thesis

Abstract

This thesis adresses a variety of early markers of

Alzheimer's disease, using MRI, histology and MRS. MRS is found to be

promising for early diagnosis of AD. However this study is done on mice and

should be replicated on AD patients over time. Besides the early markers the thesis descibes a potential difference between male and female in the development of AD in the brain.

Alzheimer's diseaseHistologyMRSMRI
Defense date
2018-10-10
Language
English
Supervisor(s)
Buchem, M.A. van
Advisor(s)
Natté, R.; Duinen, S.G. van
Committee member(s)
Weerd, L. van der; Blauw, G.J.; Rombouts, S.A.R.B.; Alia, A.; Rozemuller, A.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/66118