Obesity: exploring neural pathophysiological pathways and improving diagnostic strategies

Author(s):
Groot, C.J. de
Published
2018
Publication type
Doctoral Thesis

Abstract

This thesis describes investigations in the neural pathophysiological mechanisms leading to obesity with a specific focus on the relation of brainstructure and function with behaviour and genetics. Furthermore, it describes investigations in the diagnostic strategy in overweight and obese children.

Executive functionFTOInhibitory controlExecutive control networkSalience networkSatiety signallingImpaired glucose toleranceBone age advancementHepatic steatosis
Defense date
2018-05-29
Language
English
Supervisor(s)
Rings, E.H.H.M.
Advisor(s)
Akker, E.L.T. van den; Grond, J. van der
Committee member(s)
Pijl, H.; Rombouts, S.A.R.B.; Hokken-Koelega, A.C.; Trompet, S.
Qualification
Ph.D.
Degree granting institution
Willem-Alexander Children's Hospital, Medicine / Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/63075
ISBN(s)
9789463611008

Funding

Sponsorship
Nutricia Early Life Nutrition