Multimodal image-guided interventions using oncological biomarkers

Stammes, M.A.

Multimodal image-guided interventions using oncological biomarkers

Author(s):: Stammes, M.A.

Published: 2018
Publication type: Doctoral Thesis

Abstract

This

thesis consists of two parts addressing novel imaging technologies to improve

the treatment of cancer patients. In part I, the additional value of real time

image guidance during surgery is discussed and the research described in this part of the thesis showed that imaging performed during surgery can be of great value. Nevertheless, the success rate is highly dependent on the choice of imaging modality and biomarker to be targeted. In part II, a necrosis avid probe was successfully evaluated as novel method for early neoadjuvant treatment response monitoring.

OncologyImage-guided surgeryMultimodal imagingNecrosisTreatment evaluationFluorescenceBiomarkers

Defense date: 2018-05-22
Language: English
Supervisor(s): Geus-Oei, L.F. de
Advisor(s): Vahrmeijer, A.L.; Cruz-Ricondo, L.J.
Committee member(s): Marijnen, C.A.M.; Alves, F.; Buchem, M.A. van; Jong, M. de; Perkins, A.C.; Velde, C.J.H. van de
Qualification: Ph.D.
Degree granting institution: Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl: 1887/62351
ISBN(s): 9789090309248