Chemical tools to study the cannabinoid receptor type 2

Author(s):
Soethoudt, M.
Published
2018
Publication type
Doctoral Thesis

Abstract

The cannabinoid receptor type 2 (CB2R) is associated with

several inflammatory diseases with an unmet medical need (e.g. Alzheimers,

multiple sclerosis, reumatoid arthritis). Development of new chemical biology

strategies to study this protein is essential to aid future development of drugs for these diseases.

Cannabinoid receptorDrug discoveryChemical biologyPharmacologyPhotoaffinity labeling
Defense date
2018-04-26
Language
English
Supervisor(s)
Stelt, M. van der
Advisor(s)
Heitman, L.H.
Committee member(s)
Overkleeft, H.S.; IJzerman, A.P.; Boeckel, C.A.A. van; Witkamp, R.F.; Ioan-Facsinay, A.
Qualification
Ph.D.
Degree granting institution
Leiden Institute of Chemistry (LIC), Science, Leiden University, Leiden
hdl
1887/62061

Funding

Sponsorship
NWO