A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context

Author(s):
Elsland, D.M. van
Published
2018
Publication type
Doctoral Thesis

Abstract

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Electron microscopyCorrelative light and electron microscopyBioorthogonal chemistry
Defense date
2018-01-11
Language
English
Supervisor(s)
Overkleeft, H.S.
Advisor(s)
Kasteren, S.I. van
Committee member(s)
Berlin, I.; Briegel, A.; Koster, A.J.; Klumperman, J.; Noteborn, M.H.M.; Stelt, M. van der
Qualification
Ph.D.
Degree granting institution
Leids Instituut voor Chemisch Onderzoek, Bio-organische synthese, Science, Leiden University, Leiden
hdl
1887/61131
ISBN(s)
9789462998063