Next generation sequencing of ovarian metastases of colorectal cancer

Abstract

Patients presenting with ovarian tumors may pose diagnostic challenges. Primary ovarian tumors should be distinguished from metastases to the ovaries from other primary tumors. Treatment choices and statements about prognosis are different for localised or metastatic disease. Diagnostic workup including imaging and histologic examination of tumors is not always successful in deciphering the origin of tumors.Therefore, additional characterisation of tumors at a molecular level might be helpful.