Novel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics

Author(s):
Lange, E.C.M. de.; Brink, W.J. van den; Yamamoto, Y.; Witte, W.E.A. de (0000-0002-0840-3619); Wong, Y.C. (0000-0002-8577-3277)
Published
2017
Publication type
Article / Letter to editor
Attritionmastermind research approachphysiologically-based pharmacokinetic modeltarget occupancysystems pharmacologypharmacometabolomics
Date issued
2017-12-31
Language
English
Is part of
EXPERT OPINION ON DRUG DISCOVERY (2017), Vol. 12, no. 12, p. 1207-1218
hdl
1887/57897
doi
10.1080/17460441.2017.1380623
URL
https://doi.org/10.1080/17460441.2017.1380623