Multivariate pharmacokinetic/pharmacodynamic (PKPD) analysis with metabolomics shows multiple effects of remoxipride in rats

Author(s):
Brink, W.J. van den; Elassaiss, J.; Gonzalez Amoros, B.; Harms, A.C. (0000-0002-2931-4295); Graaf, P.H. van der; Hankemeier, T. (0000-0001-7871-2073); Lange, E.C.M. de (0000-0001-8303-1117)
Published
2017
Publication type
Article / Letter to editor
Systems pharmacologyPK/PD modelingPharmacometabolomicsBiomarkersCNS drugsD2R antagonists
Date issued
2017-11-15
Language
English
Is part of
European Journal of Pharmaceutical Sciences (2017), Vol. 109, p. 431-440
hdl
1887/57896
doi
10.1016/j.ejps.2017.08.031
URL
https://www.sciencedirect.com/science/article/pii/S0928098717304888?via=ihub