A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations

Author(s):
Yamamoto, Y.; Valitalo, P.A.J.; Berg, D.J. van den; Hartman, R.J.; Brink, W.J. van den; Wong, Y.C.; Huntjens, D.R.; Proost, J.H.; Vermeulen, A.; Krauwinkel, W.; Bakshi, S.D.; Aranzana-Climent, V.A.; Marchand, S.; Dahyot-Fizelier, C.; Couet, W.; Danhof, M.; Hasselt, J.G.C. van; Lange, E.C.M. de
Published
2017
Publication type
Article / Letter to editor
blood-brain barriercentral nervous system (CNS)human predictionpharmacokineticstranslational model
Date issued
2017
Is part of
Pharmaceutical Research (2017), Vol. 34, no. 2, p. 333-351
hdl
1887/57709