Plasma EC90 multiples are drug, target site and species specific—A physiologically based pharmacokinetic modelling example of nirmatrelvir central nervous system distribution

Author(s):
Valkengoed, D.W. van (0009-0006-7830-2553); Liu, X. (0009-0008-2017-4696); Avedissian, S.N.; Fletcher, C.V.; Brown, A.N.; Lange, E.C.M. de; Märtson, A. (0000-0001-6478-1959)
Published
2026
Publication type
Article / Letter to editor
Date issued
2026-10-23
Language
English
Publisher
Wiley
Is part of
British Journal of Pharmacology
Advanced publication
Yes
hdl
1887/5006123
doi
10.1111/bph.70717
URL
10.1111/bph.70717
URL
https://doi.org/10.1111/bph.70717