Anti sense and sensibility : renal and skin effects of (antisense) oligonucleotides

Author(s):
Meer, L. van
Published
2017
Publication type
Doctoral Thesis

Abstract

This thesis describes the clinical investigation of a novel treatment strategy for type 2 diabetes mellitus (t2dm) using an antisense oligonucleotide(aon)to inhibit the sglt2 receptor. Furthermore it describes skin effects of oligonucleotides

OligonucleotideAntisenseType 2 diabetes mellitusClinical trialPhase2study
Defense date
2017-01-19
Language
English
Supervisor(s)
Cohen, A.F.; Burggraaf, J.
Advisor(s)
Moerland, M.
Committee member(s)
Buren, M. van; Pijl, H.; Romijn, J.A.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/45389