High-resolution cryo-EM structure of integrin αIIbβ3 bound to disease-causing maternal HPA-1a antibody that blocks integrin activation

Author(s):: de Pereda J.M.; Stam W.; Gragera, M.; Meer F.W.T. van der; Chichón, F.J.; Zarkadas, E.; Schoot, E. van der; Vidarsson, G.; Takagi, J.; Margadant, C.

Published: 2026
Publication type: Article / Letter to editor

Date issued: 2026-07-17
Language: English
Publisher: American Association for the Advancement of Science (AAAS)
Is part of: Science Advances (2026), No. 29, eaed9833
hdl: 1887/4310002
doi: 10.1126/sciadv.aed9833
URL: https://doi.org/10.1126/sciadv.aed9833