Radiotherapy in cutaneous lymphomas: recommendations from the EORTC cutaneous lymphoma tumour group

Author(s):
Elsayad, K.; Guenova, E.; Assaf, C.; Nicolay, J.P.; Trautinger, F.; Stadler, R.; Waldstein, C.; Boterberg, T.; Meijnders, P.; Kirova, Y.; Dobos, G.; Duque-Santana, V.; Riggenbach, E.; Elsheshtawy, W.; Niezink, A.; Papadavid, E.; Scarisbrick, J.; Vermeer, M.; Neelis, K.J.; Bagot, M.; Battistella, M.; Quaglino, P.; Knobler, R.; Kempf, W.; Maklad, A.; Adeberg, S.; Kouloulias, V.; Simontacchi, G.; Corradini, S.; König, L.; Eich, H.T.; Cowan, R.; Correia, D.
Published
2024
Publication type
Article / Letter to editor

Abstract

The number of primary cutaneous lymphoma patients receiving low-dose radiotherapy is increasing, though controlled clinical trials defining the standard radiation dose for each specific entity have not yet been completed. Radiation oncologists are left with making highly individualized decisions that would be better enriched by additional clinical evidence. In this expert opinion, we aim to provide a clear recommendation to improve the current practice of radiation oncology. In addition, existing literature has been reviewed to develop recommendations for all types of primary cutaneous lymphoma. A prospective trial is urgently needed to identify the factors influencing patient outcomes following different radiation doses.

Primary cutaneous marginal zone lymphomaPrimary cutaneous follicular centre lymphomaPrimary cutaneous diffuse large B-celllymphomaLeg typeMycosis fungoidesSezary syndromeTotal skin electron beamHypofractionationLow-dose radiotherapy
Date issued
2024-10-16
Language
English
Publisher
ELSEVIER SCI LTD
Is part of
European Journal of Cancer
hdl
1887/4300942
doi
10.1016/j.ejca.2024.115064