Glioblastoma and the tumor microenvironment: their interaction and the impact of therapy

Author(s):
Solinge, T.S. van (0000-0003-3762-3618)
Published
2026
Publication type
Doctoral Thesis

Abstract

Glioblastoma has an intimate relationship with the tumor microenvironment, which supports tumor formation, protects against therapy, and aids in recurrence. This thesis explores the different methods of communication between the tumor and its environment, and highlights the impact of therapy on this interaction.

Neuro-oncologyGlioblastomaExtracellular vesicleLiposomeSurgeryLocal therapy
Defense date
2026-04-02
Language
English
Supervisor(s)
Broekman, M.L.D.; Peul, W.C.
Advisor(s)
Abels, E.R.
Committee member(s)
Goumans, M.J.T.H.; Koekkoek, J.A.F.; Maas, S.L.N.; Dirven, C.M.F.; Duerinck, J.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/4300399
doi
10.60602/1887-4300399
ISBN(s)
9789465360881

Funding

Sponsorship
Bontius Stichting; Stichting vrijvrouwe van Renswoude; Nijbakker-Morra; Bekker-La Bastide Fund