Incidence of γδ phenotype in mycosis fungoides: a prospective analysis

Author(s):
Kersten, J.M.; Ottevanger, R. (0000-0002-1900-4322); Jansen, P.M.; Valkema, P.A. (0000-0001-7189-4441); Schrader, A.M.R. (0000-0003-3483-0558); Quint, K.D.; Vermeer, M.H. (0000-0002-5872-4613)
Published
2025
Publication type
Article / Letter to editor

Abstract

A small subset of T-cell receptor (TCR)-delta+ cases with indolent clinical features resembling mycosis fungoides (MF) have been reported, raising debate on whether they represent MF or primary cutaneous gamma delta T-cell lymphoma (PCGDTCL) variants. To address the gap in gamma delta TCR+ cases of MF, we conducted a prospective study of patients with newly diagnosed MF. We argue that gamma delta+ MF should be incorporated as a type of MF.

Date issued
2025-08-11
Language
English
Publisher
OXFORD UNIV PRESS
Is part of
British Journal of Dermatology (2025), Vol. 193, no. 5, p. 1007-1008
hdl
1887/4298507
doi
10.1093/bjd/ljaf227