Juvenile Huntington Disease: towards better understanding its unique disease characteristics

Bakels, H.S. (2026)

Doctoral Thesis

This thesis focuses on the juvenile and pediatric Huntington Disease (HD) populations, using a translational approach to address questions regarding their epidemiology, clinical characteristics, neuropathology, and pathophysiology, in comparison to prototypical HD in adults.

• Huntington Disease
• Neurodegenerative Disease
• Pediatrics
• Neurosciences
• Neuropathology
• Neurology

• All authors: Bakels, H.S.
• Supervisor: Roos, R.A.C.; Roon-Mom, W.M.C. van
• Co-supervisor: Bot, S.T. de
• Committee: Smit, V.T.H.B.M.; Koning-Tijssen, M. de; Rozemuller, A.; Willemsen, M.A.A.P.; Vermeiren, R.R.J.M.; Dijk, J.G. van; Weerd, L. van der
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2026-02-04
• ISBN (print): 9789465228877