Tracking the vascular signature of brain tumors by exploring the field of perfusion MRI

Abstract

This thesis provides some important insights on the use of perfusion MRI in clinical practice and the steps that were taken towards optimization of DSC-MRI acquisition and image processing strategies. The studies contained in this thesis form the basis for an optimized scan protocol for glioma at 3 T and 7 T, which could be used for noninvasive characterization of the tumor type by determining the vascular signature as well as early prediction of tumor progression.