Exploring the versatility of human β-glucosidases and related glycosylated metabolites with novel chemical tools

Bannink, S. (2025)

Doctoral Thesis

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

• Gaucher Disease
• Lysosomal storage disorder
• Lipidomics
• Chemical synthesis

• All authors: Bannink, S.
• Supervisor: Aerts, J.M.F.G.
• Co-supervisor: Artola Perez de Azanza, M.E.
• Committee: Ubbink, M.; Codée, J.D.C.; Overkleeft, H.S.; Stelt, M. van der; Lefeber, D.J.; Harms, A.C.; Marques, A.R.A.
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University
• Date: 2025-10-24