The repercussions of recognition: imprints of T cells on the tumor microenvironment

Abstract

This thesis delves into the ways that T cells interact with the tumor microenvironment, the types of tumors that they can be expected to see as immunologically foreign, whether such antigen-recognition detectably leads to the specific destruction of antigen-carrying cells and how to enhance T cell activity to treat cancer patients, specifically those with triple negative breast cancer.