Serous Maculopathy due to Aspecific Choroidopathy (SMACH)

Author(s):
Dijk, E.H.C. van (0000-0002-6351-7942); Ossewaarde-van Norel, J.; Vingerling, J.R.; Cohen, S.Y.; Boon, C.J.F.
Published
2023
Publication type
Article / Letter to editor

Abstract

Macular serous subretinal fluid (SRF) has a broad differential diagnosis.1 Despite the fact that establishing a diagnosis may be challenging, the differentiation of causes of serous maculopathy is important in terms of therapeutic and prognostic consequences.1 In this paper, we describe 3 patients (Fig. 1, Supplementary Digital Content Figs. 1, 2, http://links.lww.com/APJO/A206) with a serous maculopathy due to a striking aspecific choroidopathy (thickening and hyperreflective changes), which we named serous maculopathy due to aspecific choroidopathy (SMACH). Moreover, in these patients, changes in the retinal pigment epithelium (RPE) were parallel with the choroidal irregularity, with focal hyperplastic and hyperpigmented areas. Remarkably, neither drusen nor a choroidal neovascularization could be detected on multimodal imaging. Focal leakage on fluorescein angiography was absent as well.

Date issued
2023-10-31
Language
English
Publisher
Elsevier
Is part of
Asia-Pacific Journal of Ophthalmology (2023), Vol. 12, no. 5, p. 496-498
hdl
1887/4248786
doi
10.1097/APO.0000000000000550
URL
https://www.sciencedirect.com/science/article/pii/S2162098923000439?via%3Dihub