The alkyne moiety as a latent electrophile in irreversible covalent small molecule inhibitors of Cathepsin K

Author(s):
Mons E.; Jansen, I.D.C.; Loboda, J.; Doodewaerd, B.R. van; Hermans, J.; Verdoes, M.; Boeckel, C.A.A. van (0000-0002-1576-9598); Veelen, P.A. van; Turk, B.; Turk, D.; Ovaa, H.
Published
2021
Publication type
Article / Letter to editor
Date issued
2021-03-02
Language
English
Publisher
American Chemical Society ({ACS})
Is part of
Journal of the American Chemical Society (2021), Vol. 141, no. 8, p. 3507-3514
hdl
1887/4082928
doi
10.1021/jacs.8b11027