Beyond the cloudiness in urinary tract infection: definitions, diagnostics, and strategies for prevention

Author(s):
Bilsen, M.P. (0000-0001-8877-3144)
Published
2024
Publication type
Doctoral Thesis

Abstract

This thesis describes the development of a reference standard for urinary tract infection (UTI) research. It also provides cut-off values for pyuria and novel urine biomarkers to more accurately diagnose UTI in older women. Finally, this thesis investigates intravesical aminoglycoside instillations and faecal microbiota replacement as strategies to prevent urinary tract infections in patients with recurrent UTI.

Urinary tract infectionCystitisPyelonephritisAsymptomatic bacteriuriaReference standardPyuriaUrine biomarkersAntimicrobial resistanceBladder instillationsFaecal microbiota
Defense date
2024-09-03
Language
English
Supervisor(s)
Visser, L.G.; Conroy, S.P.
Advisor(s)
Lambregts, M.M.C.
Committee member(s)
Mooijaart, S.P.; Cobbaert, C.M.; Geerlings, S.E.; Huttner, A.; Haarst, E.P. van
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/4039634
ISBN(s)
9789465061436