Small Amounts of Sub-Visible Aggregates Enhance the Immunogenic Potential of Monoclonal Antibody Therapeutics

Author(s):
Ahmadi, M.; Bryson, C.J.; Cloake, E.A.; Welch, K.; Filipe, V.; Romeijn, S.G.; Hawe, A.; Jiskoot, W. (0000-0002-1012-3456); Baker, M.P.; Fogg, M.H.
Published
2015
Publication type
Article / Letter to editor
anti-drug antibodiesbiotherapeuticsCD4(+) T cell responseshumanized antibodiesimmunogenicity
Date issued
2015-04-30
Language
English
Is part of
PHARMACEUTICAL RESEARCH (2015), Vol. 32, no. 4, p. 1383-1394
hdl
1887/38500
doi
10.1007/s11095-014-1541-x