Quantitative pharmacology approaches to inform treatment strategies against tuberculosis

Author(s):
Mehta, K.
Published
2024
Publication type
Doctoral Thesis

Abstract

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB. This PhD thesis has described how various quantitative pharmacology modeling approaches can contribute to the further development and optimization of both existing and novel therapies and treatment strategies against TB.

TuberculosisModeling and SimulationPharmacology
Defense date
2024-05-30
Language
English
Supervisor(s)
Hasselt, J.G.C. van; Graaf, P.H. van der
Committee member(s)
Irth, H.; Lange, E.C.M. de; Knibbe, C.A.J.; Svensson, E.M.; Aarnoutse, R.E.
Qualification
Ph.D.
Degree granting institution
Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University, Leiden
hdl
1887/3754903
ISBN(s)
9789465060569