Risk stratification in emergency medicine: towards improved age and sex adjusted risk assessment

Author(s):
Candel, B.G.J.
Published
2024
Publication type
Doctoral Thesis

Abstract

The growing number of older patients presenting to Emergency Departments (EDs) requires better risk stratification to guide treatment and disposition

decisions. Therefore, it is essential to understand the effect of age on the associations between physiological variables and outcomes. More importantly, most risk tools are not age or sex adjusted and are not based on a statistical approach. An age and sex adjusted risk tool could improve risk stratification in the ED.

This thesis is divided into three parts and has four aims, regarding ageadjusted interpretation of physiological variables for risk stratification in ED patients, developing a new age- and sex-adjusted risk tool for the hospital, and describing potential bias if risk tools are used for comparing the quality of care among departments.

Geriatric Emergency MedicineRisk stratificationEmergency MedicineSepsisTraumaHypertensionGeriatricsEarly Warning Score
Defense date
2024-03-14
Language
English
Supervisor(s)
Jonge, E. de
Advisor(s)
Groot, B. de
Committee member(s)
Mooijaart, S.P.; Groenewold, R.H.H.; Arbous, S.M.; Brand, C.L. van den; Brabrand, M.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3721827
ISBN(s)
9789464834086

Funding

Sponsorship
Máxima Medisch Centrum; Leiden Universitair Medisch Centrum; Nederlandse Vereniging voor Spoedeisende Hulp-artsen; Spoedeisende Geneeskunde Onderzoeksfonds