Structural biochemistry of the pentraxins

Author(s):
Noone, D.P.
Published
2024
Publication type
Doctoral Thesis

Abstract

An investigation of the complement activating pentraxin family of proteins using cryoEM and biochemical techniques.

ComplementPentraxinsC-reactive proteinCRPLong pentraxin 3PTX3C1qInnate immunitycryoEMcryo-electron microscopy
Defense date
2024-03-12
Language
English
Supervisor(s)
Koster, A.J.
Advisor(s)
Sharp, T.H.
Committee member(s)
Roumenina, L.T.; Dijke, P. ten; Trouw, L.A.; Gaboriauld, C.; Geibel, S.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3721706
ISBN(s)
9789464960310

Funding

Sponsorship
This research was supported by the following grants to Thomas H Sharp: European Research Council Grant 759517; The Netherlands Organization for Scientific Research Grants OCENW.KLEIN.291 and VI.Vidi.193.014