Substrate identification and treatment of right ventricular tachycardia: scar patterns and novel mapping tools

Author(s):
Venlet, J.
Published
2023
Publication type
Doctoral Thesis

Abstract

This thesis aims to improve the understanding and identification of the ventricular tachycardia substrate in patients with right ventricular tachycardia. An isolated epicardial right ventricular outflow tract scar is described in high level endurance athletes. Novel parameters such as endocardial unipolar voltage, transmural activation time and CT heterogeneity may help to guide substrate mapping and ablation. Implementing these techniques in current clinical practice may improve the identification and treatment of ventricular tachycardia substrates in right ventricular cardiomyopathies.

Ventricular tachycardiaArrhythmiasElectrophysiologyEndurance athletesCatheter mapping and ablationArrhythmogenic right ventricular cardiomyopathyComputed tomographyEpicardial fatVT-substrateAntiarrhythmic drug
Defense date
2023-09-07
Language
English
Supervisor(s)
Zeppenfeld, K.
Advisor(s)
Piers, S.R.D.
Committee member(s)
Blom, N.A.; Bootsma, M.; Groot, J.R. de; Riele, A.S.J.M. te; Schalij, M.J.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3638795
ISBN(s)
9789464694383

Funding

Sponsorship
ABN AMRO bank; Abbott Medical Systems Nederland; Hart onderzoek Nederland; Nederlandse hartstichting