The development of novel anti-inflammatory drugs for IBD

Author(s):
Verhaar, A.P.
Published
2015
Publication type
Doctoral Thesis

Abstract

The first part describes a non-genomic glucocorticoid action that inhibits T cell activation which was used to develop GC receptor ligands with safer profiles. The 2nd part focuses on repurposing of miltefosine as an anti-inflammatory drug in IBD.

Transfer mouse modelMiltefosineNon-transcriptionalNon-genomicGlucocorticoids
Defense date
2015-11-12
Language
English
Supervisor(s)
Hommes, D.W.; Brink, G.R. van den
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine (LUMC), Leiden University, Leiden
hdl
1887/36116
ISBN(s)
9789462331310

Funding

Sponsorship
Giuliani Pharmaceuticals