Imaging the (un)imaginable of the Barrier Immune system

Guo, N. (2023)

Doctoral Thesis

This thesis focused on investigate immune compartmentalization in the developing human intestine, and lesional⁠/healthy skin tissue from patients with mycosis fungoides and psoriasis by single-cell spectral flow cytometry, suspension mass cytometry, single-cell RNA-sequencing, functional assays, RNAscope and imaging mass cytometry⁠.

• Imaging mass cytometry
• Human intestine
• Mass cytometry
• Proliferating cells
• Mycosis Fungoides
• Psoriasis

• All authors: Guo, N.
• Supervisor: Koning, F.
• Co-supervisor: Pascutti, M.F.; Quint, K.D.
• Committee: Ossendorp, F.A.; Yazdanbakhsh, M.; Mebius, R.E.; Dijk, M.R. van
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2023-04-18
• ISBN (print): 9789464197488