Characterization of DNA-replication proteins and their molecular mechanisms: a team business

Author(s):
Botto, M.
Published
2023
Publication type
Doctoral Thesis

Abstract

This thesis investigates the characteristics and the mechanisms of DNA replicative proteins through the use of biochemistry, single molecule light mycroscopy and Cryo-EM.

DNA replicationPolymeraseSingle-moleculeCryo-EM
Defense date
2023-03-23
Language
English
Supervisor(s)
Neefjes, J.J.C.
Advisor(s)
Lamers, M.H.
Committee member(s)
Noort, S.J.T. van; Goumans, M.J.T.H.; Dekker, M.H.; Lijsterburg, M.S.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3577234