Buprenorphine: a treatment and cause of opioid-induced respiratory depression

Author(s):
Dahan, A. (0000-0003-3161-3945); Lemmen, M. van; Jansen, S.; Simons, P.; Schrier, R. van der
Published
2022
Publication type
Other

Abstract

Buprenorphine is a partial agonist at the mu opioid receptor. Due to its relatively low maximum effect on respiratory depression it is considered by some to be a safe opioid. But it can produce serious respiratory depression, particularly when combined with sedatives such as benzodiazepines.

benzodiazepinebreathingbuprenorphineopioid-induced respiratory depressionpartial agonism
Date issued
2022-03-01
Language
English
Publisher
ELSEVIER SCI LTD
hdl
1887/3572114
doi
10.1016/j.bja.2021.10.029