Modulating energy metabolism: pathophysiological aspects and novel interventions

Author(s):
Straat, M.E.
Published
2023
Publication type
Doctoral Thesis

Abstract

In this thesis, we have addressed two key objectives: 1) to gain more insight in various pathophysiological aspects of cardiometabolic diseases including in the disease prone

South Asian population, and 2) to study the physiological effects of cold exposure and identify a novel pharmacological approach to directly target BAT.

AdiposityAtherosclerosisCold exposureDyslipidemiaLipid metabolismObesityRhythm control
Defense date
2023-03-16
Language
English
Supervisor(s)
Rensen, P.C.N.
Advisor(s)
Boon, M.R.; Martinez-Tellez, B.
Committee member(s)
Yazdanbakhsh, M.; Pijl, H.; Roeters van Lennep, J.E.; Virtanen, K.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3571820
ISBN(s)
9789464589313

Funding

Sponsorship
De Nederlandse Hartstichting; Chipsoft