Systemic sclerosis: are anti-nuclear antibodies our guiding stars?

Author(s):
Boonstra, M.
Published
2022
Publication type
Doctoral Thesis

Abstract

In this thesis the role of anti-nuclear antibodies to function as biomarkers in systemic sclerosis has been evaluated. Respectively, the heterogeneity of the disease, the need for biomarkers and the role of auto-antibodies to function as such, with specific attention for anti-topoisomerase I, have been outlined in this thesis.

Auto-antibodiesBiomarkersAnti-topoisomeraseScl70
Defense date
2022-11-08
Language
English
Supervisor(s)
Huizinga, T.W.J.
Advisor(s)
Vries-Bouwstra, J.K. de
Committee member(s)
Toes, R.E.M.; Helm-van Mil, A.H.M. van der; Voskuyl, A.E.; Ninaber, M.K.; Bultink, I.E.M.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3485292

Funding

Sponsorship
Boehringer Ingelheim; Chipsoft; Stichting NVLE fonds