The ins and outs of mutlivesicular bodies

Author(s):
Perrin, P.C.
Published
2022
Publication type
Doctoral Thesis

Abstract

In this thesis I explored the ins and outs of the multivesicular body, the pathways that intersect at this central endocytic compartment, the dynamics governing its lumen and how such processes impact various fields of cell biology and disease.

EndosomeLysosomeMultivesicular bodyIntraluminal vesicleExtracellular vesicleExosomeEndolysosomeRetrofusionEndocytic networkMHC class II
Defense date
2022-10-27
Language
English
Supervisor(s)
Neefjes, J.J.C.
Advisor(s)
Berlin, I.
Committee member(s)
Dijke, P. ten; Borst, J.G.; Kant, R. van der; Reits, E.A.
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/3484871
ISBN(s)
9789464586497